Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides

The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an unsolved problem despite their significant synthetic potential. Here, the authors show that alkyl chlorides can efficiently participate in Mizoroki–Heck cross-coupling reactions with excellent functional group com...

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Bibliographic Details
Main Authors: Geun Seok Lee, Daeun Kim, Soon Hyeok Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21270-9