Inhibition of Tumor Angiogenesis and Tumor Growth by the DSL Domain of Human Delta-Like 1 Targeted to Vascular Endothelial Cells

The growth of solid tumors depends on neovascularization. Several therapies targeting tumor angiogenesis have been developed. However, poor response in some tumors and emerging resistance necessitate further investigations of newdrug targets. Notch signal pathway plays a pivotal role in vascular de...

Full description

Bibliographic Details
Main Authors: Xing-Cheng Zhao, Guo-Rui Dou, Li Wang, Liang Liang, Deng-Mei Tian, Xiu-Li Cao, Hong-Yan Qin, Chun-Mei Wang, Ping Zhang, Hua Han
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800759