Disparate effects of gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia
The Src homology-2 domain protein B is an adaptor protein operating downstream of tyrosine kinases. The Shb gene knockout has been found to accelerate p210 Breakpoint cluster region-cAbl oncogene 1 tyrosine kinase-induced leukemia. In human myeloid leukemia were tumors with high Src homology-2 domai...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IOS Press
2018-04-01
|
| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428318771472 |