Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy

Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy

Acrylamide (ACR) is a common chemical used in various industries and it said to have chronic neurotoxic effects. It is produced during tobacco smoking and is also generated in high-starch foods during heat processing. Notoginsenoside R1 (NR1) is a traditional Chinese medicine, which is used to impro...

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Bibliographic Details
Main Authors: Wenjun Wang, Lu Huang, Elizabeth Rosalind Thomas, Yingying Hu, Fancai Zeng, Xiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
acrylamide
notoginsenoside r1
thioredoxin-1
autophagy
integrin alpha V
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.559046/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.559046/full

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