Development of a New Internally Controlled One-Step Real-Time RT-PCR for the Molecular Detection of Enterovirus A71 in Africa and Madagascar

Development of a New Internally Controlled One-Step Real-Time RT-PCR for the Molecular Detection of Enterovirus A71 in Africa and Madagascar

Enterovirus A71 (EV-A71) is a leading cause of hand-foot-and-mouth disease (HFMD) and can be associated with severe neurological complications. EV-A71 strains can be classified into seven genogroups, A-H, on the basis of the VP1 capsid protein gene sequence. Genogroup A includes the prototype strain...

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Bibliographic Details
Main Authors: Romain Volle, Marie-Line Joffret, Kader Ndiaye, Maria Dolores Fernandez-Garcia, Richter Razafindratsimandresy, Jean-Michel Heraud, Dorra Rezig, Serge Alain Sadeuh-Mba, Leila Boulahbal-Anes, Mohamed Seghier, Jagadish M. Deshpandeh, Maël Bessaud, Francis Delpeyroux
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
enterovirus 71
EV-A71
HFMD
new genogroups
molecular detection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01907/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01907/full

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