Structural Design, Synthesis, and Preliminary Biological Evaluation of Novel Dihomooxacalix[4]arene-Based Anti-tumor Agents

Structural Design, Synthesis, and Preliminary Biological Evaluation of Novel Dihomooxacalix[4]arene-Based Anti-tumor Agents

Calixarene and its derivatives have extensively served as promising anti-tumor agents. Previously, we have synthesized a series of calix[n]arene polyhydroxyamine derivatives (n = 4, 6, 8) and found that 5,11,17,23-tetra-tert-butyl-25,27-bis [N-(2-hydroxyethyl)aminocarbonylmethoxyl] calix[4]arene (CL...

Full description

Bibliographic Details
Main Authors: Lin An, Chan Wang, Lili Han, Jiadong Liu, Tonghui Huang, Youguang Zheng, Chaoguo Yan, Jing Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Chemistry
Subjects:
supramolecular chemotherapy
calixarene
structural optimization
dihomooxacalix[4]arene
X-ray diffraction
biological evaluation
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00856/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00856/full

Similar Items