Nucleosome Presence at AML-1 Binding Sites Inversely Correlates with Ly49 Expression: Revelations from an Informatics Analysis of Nucleosomes and Immune Cell Transcription Factors.

Beyond its role in genomic organization and compaction, the nucleosome is believed to participate in the regulation of gene transcription. Here, we report a computational method to evaluate the nucleosome sensitivity for a transcription factor over a given stretch of the genome. Sensitive factors ar...

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Bibliographic Details
Main Authors: Andrew Wight, Doo Yang, Ilya Ioshikhes, Andrew P Makrigiannis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4849748?pdf=render