CDK1 and CCNB1 as potential diagnostic markers of rhabdomyosarcoma: validation following bioinformatics analysis

CDK1 and CCNB1 as potential diagnostic markers of rhabdomyosarcoma: validation following bioinformatics analysis

Abstract Background Rhabdomyosarcoma (RMS), a common soft-tissue malignancy in pediatrics, presents high invasiveness and mortality. However, besides known changes in the PAX3/7-FOXO1 fusion gene in alveolar RMS, the molecular mechanisms of the disease remain incompletely understood. The purpose of...

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Bibliographic Details
Main Authors: Qianru Li, Liang Zhang, Jinfang Jiang, Yangyang Zhang, Xiaomeng Wang, Qiaochu Zhang, Yang Wang, Chunxia Liu, Feng Li
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Genomics
Subjects:
Rhabdomyosarcoma
Hub genes
Diagnosis
CDK1
CCNB1
Bioinformatics analysis
Online Access:https://doi.org/10.1186/s12920-019-0645-x

Internet

https://doi.org/10.1186/s12920-019-0645-x

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