Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults

Background: Circulating peripheral blood mononuclear cells (PBMCs) are exposed to metabolic and immunological stimuli that influence their functionality. We hypothesized that prevailing vitamin D status [25(OH)D] would modulate the bioenergetic profile of PBMCs derived from humans. Materials and met...

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Bibliographic Details
Main Authors: Emily K. Calton, Kevin N. Keane, Mario J. Soares, Jordan Rowlands, Philip Newsholme
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716301951