Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications

Viruses interplay with the host SUMOylation system to manipulate diverse cellular responses. The Ad E4-ORF3 protein forms a dynamic nuclear network to interfere with and exploit different host processes, including the DNA damage and interferon responses. We previously reported that E4-ORF3 is a SUMO...

Full description

Bibliographic Details
Main Authors: Sook-Young Sohn, Patrick Hearing
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00022-19