Preclinical Evaluation of Radioiodinated Hoechst 33258 for Early Prediction of Tumor Response to Treatment of Vascular-Disrupting Agents

This study aimed to explore the use of 131I-Hoechst 33258 (131I-H33258) for early prediction of tumor response to vascular-disrupting agents (VDAs) with combretastatin-A4 phosphate (CA4P) as a representative. Necrosis avidity of 131I-H33258 was evaluated in mouse models with muscle necrosis and bloc...

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Bibliographic Details
Main Authors: Dongjian Zhang, Meng Gao, Nan Yao, Cuihua Jiang, Wei Liu, Tiannv Li, Shaoli Song, Dejian Huang, Zhiqi Yin, Yunliang Qiu, Qiaomei Jin
Format: Article
Language:English
Published: Hindawi-Wiley 2018-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2018/5237950