Synthesis of Functionalized Indoles via Palladium-Catalyzed Cyclization of <i>N</i>-(2-allylphenyl) Benzamide: A Method for Synthesis of Indomethacin Precursor
We developed an efficient method for synthesis of substituted <i>N</i>-benzoylindole via Pd(II)-catalyzed C−H functionalization of substituted <i>N</i>-(2-allylphenyl)benzamide. The reaction showed a broad substrate scope (including <i>N</i>-acetyl and &...
Main Authors: | Zhe Chang, Tong Ma, Yu Zhang, Zheng Dong, Heng Zhao, Depeng Zhao |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/5/1233 |
Similar Items
-
Synthesis of Indoles via Intermolecular and Intramolecular Cyclization by Using Palladium-Based Catalysts
by: Ayesha, et al.
Published: (2021-08-01) -
Synthesis of Some New Amides Derived from Indomethacin
by: Kawther Al-Naimi, et al.
Published: (2013-12-01) -
Palladium-catalyzed regio- and stereoselective synthesis of aryl and 3-indolyl-substituted 4-methylene-3,4-dihydroisoquinolin-1(2H)-ones
by: Valeria Nori, et al.
Published: (2020-05-01) -
Pd/C-Mediated synthesis of indoles in water
by: Mohosin Layek, et al.
Published: (2009-09-01) -
Mechanistic Studies for Synthesis of Bis(indolyl)methanes: Pd-Catalyzed C–H Activation of Indole–Carboxylic Acids with Benzyl Alcohols in Water
by: Yuusaku Yokoyama, et al.
Published: (2013-05-01)