Modulation of signal strength switches Notch from an inducer of T cells to an inducer of ILC2

Modulation of signal strength switches Notch from an inducer of T cells to an inducer of ILC2

Innate lymphoid cells (ILC) are emerging key players of the immune system with close lineage relationship to T cells. ILC2 play an important role in protective immunity against multicellular parasites, but are also involved in the pathogenesis of type 2 immune diseases. Here, we have studied the dev...

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Bibliographic Details
Main Authors: Rebecca eGentek, J. Marius Munneke, Christina eHelbig, Bianca eBlom, Mette D Hazenberg, Hergen eSpits, Derk eAmsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
human
T cells
innate lymphoid cells
Notch
Thymus
ILC2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00334/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00334/full

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