The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature

The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature

Canonical or classical transient receptor potential channel 6 (TRPC6) is a Ca2+-permeable non-selective cation channel that is widely expressed in the heart, lung, and vascular tissues. The use of TRPC6-deficient (“knockout”) mice has provided important insights into the role of TRPC6 in normal phys...

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Bibliographic Details
Main Authors: Monika Malczyk, Alexandra Erb, Christine Veith, Hossein Ardeschir Ghofrani, Ralph T. Schermuly, Thomas Gudermann, Alexander Dietrich, Norbert Weissmann, Akylbek Sydykov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
transient receptor potential channels
transient receptor potential channel 6
hypoxic pulmonary vasoconstriction
pulmonary hypertension
vascular permeability
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00707/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00707/full

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