A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC

Abstract Our previous work identified a 13-gene miRNA signature predictive of response to the epidermal growth factor receptor (EGFR) inhibitor, erlotinib, in Non-Small Cell Lung Cancer cell lines. Bioinformatic analysis of the signature showed a functional convergence on TGFβ canonical signalling....

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Bibliographic Details
Main Authors: Madeline Krentz Gober, James P. Collard, Katherine Thompson, Esther P. Black
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04097-7