Vaccination with Single Plasmid DNA Encoding IL-12 and Antigens of Severe Fever with Thrombocytopenia Syndrome Virus Elicits Complete Protection in IFNAR Knockout Mice
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by SFTS virus (SFTSV) infection. Despite the gradual increase in SFTS cases and high mortality in the endemic region, no specific viral therapy nor vaccine is available. Here, we developed single recombinant...
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Format: | Article |
Language: | English |
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MDPI AG
2020-06-01
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Series: | Proceedings |
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Online Access: | https://www.mdpi.com/2504-3900/50/1/104 |