Vaccination with Single Plasmid DNA Encoding IL-12 and Antigens of Severe Fever with Thrombocytopenia Syndrome Virus Elicits Complete Protection in IFNAR Knockout Mice

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by SFTS virus (SFTSV) infection. Despite the gradual increase in SFTS cases and high mortality in the endemic region, no specific viral therapy nor vaccine is available. Here, we developed single recombinant...

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Bibliographic Details
Main Author: Nam-Hyuk Cho
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/50/1/104