A Novel Computational Approach for Identifying Essential Proteins From Multiplex Biological Networks

A Novel Computational Approach for Identifying Essential Proteins From Multiplex Biological Networks

The identification of essential proteins can help in understanding the minimum requirements for cell survival and development. Ever-increasing amounts of high-throughput data provide us with opportunities to detect essential proteins from protein interaction networks (PINs). Existing network-based a...

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Bibliographic Details
Main Authors: Bihai Zhao, Sai Hu, Xiner Liu, Huijun Xiong, Xiao Han, Zhihong Zhang, Xueyong Li, Lei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
identification of essential proteins
protein interaction network
tensor
multiplex biological networks
random walk
Markov chain
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00343/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00343/full

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