Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers

Abstract Maytenus roylanus (MEM) is a plant with anti-proliferative effects against prostate cancer. We aimed to explore the mechanism of action of MEM in prostate cancer (PCa) by employing an in vitro global proteome approach to get useful information of various signaling pathways and effected gene...

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Bibliographic Details
Main Authors: Maria Shabbir, Hasan Mukhtar, Deeba Syed, Suhail Razak, Tayyaba Afsar, Ali Almajwal, Yasmin Badshah, Dara Aldisi
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91408-8