Genome-wide mRNA profiling identifies the NRF2-regulated lymphocyte oxidative stress status in patients with silicosis

Abstract Background The immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative stress state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2)-regulated antioxidant genes in peripher...

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Bibliographic Details
Main Authors: Yingzheng Zhao, Guangcui Xu, Haibin Li, Meiyu Chang, Cheng Xiong, Yingjun Tao, Yi Guan, Yuchun Li, Sanqiao Yao
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Occupational Medicine and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12995-021-00332-0