On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway

DNA replication in eukaryotes is achieved by the activation of multiple replication origins which needs to be precisely coordinated in space and time. This spatio-temporal replication program is regulated by many factors to maintain genome stability, which is frequently threatened through stresses o...

Full description

Bibliographic Details
Main Authors: Diletta Ciardo, Arach Goldar, Kathrin Marheineke
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Genes
Subjects:
ATR
MBT
Online Access:https://www.mdpi.com/2073-4425/10/2/94