The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain
<p>Abstract</p> <p>Background</p> <p>High-mobility group box-1 protein (HMGB1) is a nuclear protein that regulates gene expression throughout the body. It can also become cytoplasmic and function as a neuromodulatory cytokine after tissue damage or injury. The manner in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-07-01
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Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/9/1/180 |