Direct Detection and Discrimination of Nucleotide Polymorphisms Using Anthraquinone Labeled DNA Probes

Direct Detection and Discrimination of Nucleotide Polymorphisms Using Anthraquinone Labeled DNA Probes

A novel electrochemical detection approach using DNA probes labeled with Anthraquinone (AQ) as a reporter moiety has been successfully exploited as a method for the direct detection of DNA targets. This assay uses simple voltammetry techniques (Differential Pulse Voltammetry) to exploit the unique r...

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Bibliographic Details
Main Authors: Sarah A. Goodchild, Rachel Gao, Daniel P. Shenton, Alastair J. S. McIntosh, Tom Brown, Philip N. Bartlett
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Chemistry
Subjects:
DNA hybridization
redox reporter
anthraquinone
nucleotide polymorphisms
diagnostics
environmental surveillance
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00381/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00381/full

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