Human axial progenitors generate trunk neural crest cells in vitro

Human axial progenitors generate trunk neural crest cells in vitro

The neural crest (NC) is a multipotent embryonic cell population that generates distinct cell types in an axial position-dependent manner. The production of NC cells from human pluripotent stem cells (hPSCs) is a valuable approach to study human NC biology. However, the origin of human trunk NC rema...

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Bibliographic Details
Main Authors: Thomas JR Frith, Ilaria Granata, Matthew Wind, Erin Stout, Oliver Thompson, Katrin Neumann, Dylan Stavish, Paul R Heath, Daniel Ortmann, James OS Hackland, Konstantinos Anastassiadis, Mina Gouti, James Briscoe, Valerie Wilson, Stuart L Johnson, Marysia Placzek, Mario R Guarracino, Peter W Andrews, Anestis Tsakiridis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
axial progenitors
neural crest
pluripotent stem cells
In vitro differentiation
embryonic development
neuromesodermal progenitors
Online Access:https://elifesciences.org/articles/35786

Internet

https://elifesciences.org/articles/35786

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