The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells.

Jesridonin, a small molecule obtained through the structural modification of Oridonin, has extensive antitumor activity. In this study, we evaluated both its in vitro activity in the cancer cell line EC109 and its in vivo effect on tumor xenografts in nude mice. Apoptosis induced by Jesridonin was d...

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Bibliographic Details
Main Authors: Cong Wang, Liping Jiang, Saiqi Wang, Hongge Shi, Junwei Wang, Ran Wang, Yongmei Li, Yinhui Dou, Ying Liu, Guiqin Hou, Yu Ke, Hongmin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4477902?pdf=render