RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer.

RNA-binding proteins (RBPs) associate with the primary, precursor, and mature microRNAs, which in turn control post-transcriptional gene regulation. Here, by small RNAseq, we show that RBP FXR1 controls the expression of a subset of mature miRNAs, including highly expressed miR301a-3p in oral cancer...

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Bibliographic Details
Main Authors: Mrinmoyee Majumder, Viswanathan Palanisamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008580