Searching for tissue-specific expression pattern-linked nucleotides of UGT1A isoforms.

UDP-glucuronosyltransferases 1A isoforms belong to a superfamily of microsomal enzymes responsible for glucuronidation of numerous endogenous and exogenous compounds. The nine functional UGT1A isoforms are encoded by a single UGT1A gene locus with multiple first exons. The expression of the UGT1A tr...

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Bibliographic Details
Main Authors: Wei Zhang, Wanqing Liu, Federico Innocenti, Mark J Ratain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1851988?pdf=render