Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration

Many brain pathologies are associated with liver damage, but a direct link has long remained elusive. Here, we establish a new paradigm for interrogating brain-periphery interactions by leveraging zebrafish for its unparalleled access to the intact whole animal for in vivo analysis in real time afte...

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Bibliographic Details
Main Authors: Linlin Yang, Jessica A Jiménez, Alison M Earley, Victoria Hamlin, Victoria Kwon, Cameron T Dixon, Celia E Shiau
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/58191