Restored TDCA and valine levels imitate the effects of bariatric surgery

Background: Obesity is widespread and linked to various co-morbidities. Bariatric surgery has been identified as the only effective treatment, promoting sustained weight loss and the remission of co-morbidities. Methods: Metabolic profiling was performed on diet-induced obese (DIO) mice, lean mice,...

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Main Authors: Markus Quante, Jasper Iske, Timm Heinbokel, Bhavna N Desai, Hector Rodriguez Cetina Biefer, Yeqi Nian, Felix Krenzien, Tomohisa Matsunaga, Hirofumi Uehara, Ryoichi Maenosono, Haruhito Azuma, Johann Pratschke, Christine S Falk, Tammy Lo, Eric Sheu, Ali Tavakkoli, Reza Abdi, David Perkins, Maria-Luisa Alegre, Alexander S Banks, Hao Zhou, Abdallah Elkhal, Stefan G Tullius
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
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Online Access:https://elifesciences.org/articles/62928