Molecular mechanics of the alpha-actinin rod domain: bending, torsional, and extensional behavior.

alpha-Actinin is an actin crosslinking molecule that can serve as a scaffold and maintain dynamic actin filament networks. As a crosslinker in the stressed cytoskeleton, alpha-actinin can retain conformation, function, and strength. alpha-Actinin has an actin binding domain and a calmodulin homology...

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Bibliographic Details
Main Authors: Javad Golji, Robert Collins, Mohammad R K Mofrad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2676514?pdf=render