Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells

Inhibition of Heparanase Expression Results in Suppression of Invasion, Migration and Adhesion Abilities of Bladder Cancer Cells

Heparan sulfate proteoglycan syndecan-1, CD138, is known to be associated with cell proliferation, adhesion, and migration in malignancies. We previously reported that syndecan-1 (CD138) may contribute to urothelial carcinoma cell survival and progression. We investigated the role of heparanase, an...

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Bibliographic Details
Main Authors: Yoshihiro Tatsumi, Makito Miyake, Keiji Shimada, Tomomi Fujii, Shunta Hori, Yosuke Morizawa, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Noboru Konishi, Kiyohide Fujimoto
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
heparanase
syndecan-1
heparan sulfate proteoglycans (HSPGs), urothelial carcinoma
Online Access:https://www.mdpi.com/1422-0067/21/11/3789

Internet

https://www.mdpi.com/1422-0067/21/11/3789

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