The Emergence of the Dose–Response Concept in Biology and Medicine
A historical assessment of the origin of the dose–response in modern toxicology and its integration as a central concept in biology and medicine is presented. This article provides an overview of how the threshold, linear and biphasic (i.e., hormetic) dose–response models emerged in the late 19th an...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-12-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/17/12/2034 |