The role of natural killer cells in chronic myeloid leukemia

The role of natural killer cells in chronic myeloid leukemia

Chronic myeloid leukemia is a neoplasia resulting from a translocation between chromosomes 9 and 22 producing the BCR-ABL hybrid known as the Philadelphia chromosome (Ph). In chronic myeloid leukemia a proliferation of malignant myeloid cells occurs in the bone marrow due to excessive tyrosine kinas...

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Bibliographic Details
Main Authors: Anna Carolyna Araújo Danier, Ricardo Pereira de Melo, Marcelo Henrique Napimoga, Maria Theresa Cerávolo Laguna-Abreu
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Leukemia, myelogenous, chronic, BCR-ABL Positive
Killer cells, natural
killer cell lectin-like receptor subfamily D
Protein kinase inhibitors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000300015

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000300015

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