Total flavonoids of rhizoma drynariae ameliorates bone formation and mineralization in BMP-Smad signaling pathway induced large tibial defect rats

Total flavonoids of rhizoma drynariae ameliorates bone formation and mineralization in BMP-Smad signaling pathway induced large tibial defect rats

Osteogenesis and angiogenesis acts as an essential role in repairing large tibial defects (LTDs). Total flavonoids of rhizoma drynariae (TFRD), a traditional Chinese medicinal herb, is reported to show anabolic effects on fracture healing. However, whether TFRD could improve the bone formation and a...

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Bibliographic Details
Main Authors: Weipeng Sun, Minying Li, Yan Zhang, Yingjie Huang, Qunzhang Zhan, Yueyi Ren, Hang Dong, Jiena Chen, Zige Li, Chun Fan, Feng Huang, Zhen Shen, Ziwei Jiang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bone formation
BMP-Smad signaling pathway
Large tibial defects
Mineralization
Total flavonoids of rhizoma drynariae
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221002651

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http://www.sciencedirect.com/science/article/pii/S0753332221002651

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