Identification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library

The application of a cell-based growth inhibition on a library of skeletally different glycomimetics allowed for the selection of a hexahydro-2H-furo[3,2-b][1,4]oxazine compound as candidate inhibitors of MDA-MB-231 cell growth. Subsequent synthesis of analogue compounds and preliminary biological s...

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Bibliographic Details
Main Authors: Elena Lenci, Riccardo Innocenti, Alessio Biagioni, Gloria Menchi, Francesca Bianchini, Andrea Trabocchi
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/10/1405