Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans.
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a devastating complication of numerous underlying conditions, most notably sepsis. Although pathologic vascular leak has been implicated in the pathogenesis of ARDS and sepsis-associated lung injury, the mechanisms promoting leak are incomple...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-03-01
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| Series: | PLoS Medicine |
| Online Access: | http://europepmc.org/articles/PMC1334221?pdf=render |