Deletion of <i>Trpm4</i> Alters the Function of the Na<sub>v</sub>1.5 Channel in Murine Cardiac Myocytes

Deletion of <i>Trpm4</i> Alters the Function of the Na<sub>v</sub>1.5 Channel in Murine Cardiac Myocytes

Transient receptor potential melastatin member 4 (TRPM4) encodes a Ca<sup>2+</sup>-activated, non-selective cation channel that is functionally expressed in several tissues, including the heart. Pathogenic mutants in <i>TRPM4</i> have been reported in patients with inherited...

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Bibliographic Details
Main Authors: Lijo Cherian Ozhathil, Jean-Sébastien Rougier, Prakash Arullampalam, Maria C. Essers, Daniela Ross-Kaschitza, Hugues Abriel
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
TRPM4
SCN5A
intracardiac ECG
mexiletine
cardiac conduction disorder
channelosome
Online Access:https://www.mdpi.com/1422-0067/22/7/3401

Internet

https://www.mdpi.com/1422-0067/22/7/3401

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