Cancer quasispecies and stem-like adaptive aneuploidy [v1; ref status: indexed, http://f1000r.es/29s]

In this paper we develop a theoretical frame to understand self-regulation of aneuploidy rate in cancer and stem cells. This is accomplished building upon quasispecies theory, by leaving its formal mathematical structure intact, but by drastically changing the meaning of its objects. In particular,...

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Bibliographic Details
Main Authors: Domenico Napoletani, Michele Signore, Daniele C Struppa
Format: Article
Language:English
Published: F1000 Research Ltd 2013-12-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/2-268/v1