Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil

Sickle cell disease (SCD) is one of the most prevalent and severe monogenetic disorders, affecting several million people around the world. Clinical manifestations and complications of the disease include sickle cell pain crisis, silent cerebral infarct, stroke, nephropathy and early death. In this...

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Main Authors: Gabriele Louise Soares Martins, Bruno Diaz Paredes, Carine Machado Azevedo, Gabriela Louise De Almeida Sampaio, Carolina Kymie Vasques Nonaka, Bruno Raphael Ribeiro Cavalcante, Katia Nunes Da Silva, Ciro Silveira E. Pereira, Milena Botelho Pereira Soares, Ricardo Ribeiro Dos Santos, Bruno Solano De Freitas Souza
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118302356