Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

<p>Abstract</p> <p>Background</p> <p>Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not unc...

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Bibliographic Details
Main Authors: Armstrong Stephen R, Narendrula Rashmi, Guo Baoqing, Parissenti Amadeo M, McCallum Katherine L, Cull Stephanie, Lannér Carita
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Journal of Ovarian Research
Subjects:
Online Access:http://www.ovarianresearch.com/content/5/1/40