Investigation of the chromosome regions with significant affinity for the nuclear envelope in fruit fly--a model based approach.

Three dimensional nuclear architecture is important for genome function, but is still poorly understood. In particular, little is known about the role of the "boundary conditions"--points of attachment between chromosomes and the nuclear envelope. We describe a method for modeling the 3D o...

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Bibliographic Details
Main Authors: Nicholas Allen Kinney, Igor V Sharakhov, Alexey V Onufriev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3961273?pdf=render