Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model.

Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model.

Glioblastoma, the most aggressive form of glioma, has a 5-year survival rate of <5%. While radiation and immunotherapies are routinely studied in the murine Gl261 glioma model, little is known about its inherent immune response. This study quantifies the temporal and spatial localization of immun...

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Bibliographic Details
Main Authors: Kelly J McKelvey, Amanda L Hudson, Ramyashree Prasanna Kumar, James S Wilmott, Grace H Attrill, Georgina V Long, Richard A Scolyer, Stephen J Clarke, Helen R Wheeler, Connie I Diakos, Viive M Howell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226444

Internet

https://doi.org/10.1371/journal.pone.0226444

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