Cisplatin Protects against Acute Liver Failure by Inhibiting Nuclear HMGB1 Release

Cisplatin is one of the most widely used chemical drugs for anticancer treatment. Recent studies have focused on the ability of cisplatin to retain the high mobility group box 1 (HMGB1) protein in cisplatin-DNA adducts, thereby preventing its release from the nucleus. Because HMGB1 is a powerful inf...

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Bibliographic Details
Main Authors: Zuo-Jiong Gong, Fan Yang, Xiao-Qun Han, Lu-Wen Wang, Li-Kun Wang, Xun Li
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/6/11224