Rapid cytoskeletal response of epithelial cells to force generation by type IV pili.

Many bacterial pathogens interfere with cellular functions including phagocytosis and barrier integrity. The human pathogen Neissieria gonorrhoeae generates grappling hooks for adhesion, spreading, and induction of signal cascades that lead to formation cortical plaques containing f-actin and ezrin....

Full description

Bibliographic Details
Main Authors: Dirk Opitz, Berenike Maier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3038865?pdf=render