Hair Analysis for Determination of Isoniazid Concentrations and Acetylator Phenotype during Antituberculous Treatment

Background. Analysis of isoniazid (INH) uptake has been based on measurement of plasma concentrations providing a short-term and potentially biased view. Objectives. To establish hair analysis as a tool to measure long-term uptake of INH and to assess whether acetylator phenotype in hair reflects N-...

Full description

Bibliographic Details
Main Authors: Michael Eisenhut, Detlef Thieme, Dagmar Schmid, Sybille Fieseler, Hans Sachs
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Tuberculosis Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/327027