Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection.

Chronic infections are an increasing problem due to the aging population and the increase in antibiotic resistant organisms. Therefore, understanding the host-pathogen interactions that result in chronic infection is of great importance. Here, we investigate the molecular basis of chronic bacterial...

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Bibliographic Details
Main Authors: Thomas J Hannan, Indira U Mysorekar, Chia S Hung, Megan L Isaacson-Schmid, Scott J Hultgren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2930321?pdf=render