Perspectives on ROCK2 as a Therapeutic Target for Alzheimer’s Disease

Rho-associated coiled-coil containing kinase isoform 2 (ROCK2) is a member of the AGC family of serine/threonine kinases and an extensively studied regulator of actin-mediated cytoskeleton contractility. Over the past decade, new evidence has emerged that suggests ROCK2 regulates autophagy. Recent s...

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Bibliographic Details
Main Authors: Audrey J. Weber, Jeremy H. Herskowitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.636017/full