Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain

<p>Abstract</p> <p>Background</p> <p>Scaffold proteins have an important role in the regulation of signal propagation. These proteins do not possess any enzymatic activity but can contribute to the formation of multiprotein complexes. Although scaffold proteins are pres...

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Bibliographic Details
Main Authors: Pesti Szabolcs, Balázs Annamária, Udupa Roopesh, Szabó Beáta, Fekete Anna, Bőgel Gábor, Buday László
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Cell Communication and Signaling
Subjects:
Nck
Online Access:http://www.biosignaling.com/content/10/1/36