Amantadine Alleviates Postoperative Cognitive Dysfunction Possibly by Preserving Neurotrophic Factor Expression and Dendritic Arborization in the Hippocampus of Old Rodents

Amantadine Alleviates Postoperative Cognitive Dysfunction Possibly by Preserving Neurotrophic Factor Expression and Dendritic Arborization in the Hippocampus of Old Rodents

ObjectivesAmantadine has been shown to attenuate postoperative learning and memory dysfunction in young adult rats. However, postoperative cognitive dysfunction often occurs in elderly patients. We aimed to determine whether amantadine attenuated postoperative learning and memory dysfunction and whe...

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Bibliographic Details
Main Authors: Jing Zhong, Jun Li, Cheng Ni, Zhiyi Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
amantadine
dendritic arborization
neurotrophic factors
old rodents
postoperative cognitive dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.605330/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2020.605330/full

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