Metformin inhibits cell proliferation in SKM-1 cells via AMPK-mediated cell cycle arrest

Metformin, a widely used antidiabetic drug, has previously been demonstrated to exert anti-cancer effects in certain hematological malignancies, but its effects on the transformation of myelodysplastic syndromes to acute myeloid leukemia (AML-MDS) remain unclear. The present study aimed to investiga...

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Bibliographic Details
Main Authors: Xiaojia Zhou, Yunchun Kuang, Simin Liang, Li Wang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319357214