Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data.

Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data.

Diffusion tensor imaging (DTI) based assessment of white matter fiber tract integrity can support the diagnosis of Alzheimer's disease (AD). The use of DTI as a biomarker, however, depends on its applicability in a multicenter setting accounting for effects of different MRI scanners. We applied...

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Bibliographic Details
Main Authors: Martin Dyrba, Michael Ewers, Martin Wegrzyn, Ingo Kilimann, Claudia Plant, Annahita Oswald, Thomas Meindl, Michela Pievani, Arun L W Bokde, Andreas Fellgiebel, Massimo Filippi, Harald Hampel, Stefan Klöppel, Karlheinz Hauenstein, Thomas Kirste, Stefan J Teipel, EDSD study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3669206?pdf=render

Internet

http://europepmc.org/articles/PMC3669206?pdf=render

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